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Description
Carbonic Anhydrase 9 Recombinant Rabbit mAb (SDT-733-28)Product Specification Host Rabbit Synonyms Carbonate dehydratase IX, Carbonic anhydrase IX (CA IX; CAIX), Membrane antigen MN, P54 58N, Renal cell carcinoma associated antigen G250 (RCC associated antigen G250), pMW1, CA9, G250, MN Immunogen Synthetic Peptide Location Cell membrane Accession Q16790 Clone Number SDT 733 28 Antibody Type Recombinant mAb Isotype IgG Application WB, IHC P Reactivity Hu Purification Protein A Concentration 0. 5 mg ml
Product Specification
| Host | Rabbit |
| Synonyms | Carbonate dehydratase IX, Carbonic anhydrase IX (CA-IX; CAIX), Membrane antigen MN, P54/58N, Renal cell carcinoma-associated antigen G250 (RCC-associated antigen G250), pMW1, CA9, G250, MN |
| Immunogen | Synthetic Peptide |
| Location | Cell membrane |
| Accession | Q16790 |
| Clone Number | SDT-733-28 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB, IHC-P |
| Reactivity | Hu |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05%BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | |
| IHC-P | 1:500 |
Background
Carbonic anhydrase IX (CA9/CAIX) is an enzyme encoded by the CA9 gene. It is one of the 14 subtypes of carbonic anhydrase discovered by humans, a transmembrane dimer metalloenzyme with extracellular active sites that promote gastrointestinal acid secretion. CAIX is overexpressed in many types of cancers, including clear cell renal cell carcinoma (RCC), cervical cancer, breast cancer, and lung cancer. In these cancers, CAIX promotes tumor growth by enhancing tumor acidosis.
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Exchange/Return Notes
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