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Description
Biotinylated FcRn His&Avi Tag Protein, CynomolgusProduct Specification Species Cynomolgus Synonyms FcRn; FCGRT & B2M Accession Q8SPV9(FcGRT)Q8SPW0(B2M) Amino Acid Sequence Ala24 Ser297 (FcRn); Ile21 Met119 (B2M), with C terminal His and Avi tag Expression System HEK293 Molecular Weight 33 40 &10 15kDa (Reducing) Purity 95% by SDS PAGE Endotoxin <1EU g Conjugation Biotin Tag Avi Tag, His Tag Physical Appearance Lyophilized Powder Storage Buffer PBS, pH7. 4. Reconstitution Reconstitute at 0. 1 1 mg ml
Product Specification
| Species | Cynomolgus |
| Synonyms | FcRn; FCGRT & B2M |
| Accession | Q8SPV9(FcGRT)、Q8SPW0(B2M) |
| Amino Acid Sequence | Ala24-Ser297 (FcRn);Ile21-Met119 (B2M), with C-terminal His and Avi tag |
| Expression System | HEK293 |
| Molecular Weight | 33-40 &10-15kDa (Reducing) |
| Purity | ＞95% by SDS-PAGE |
| Endotoxin | <1EU/μg |
| Conjugation | Biotin |
| Tag | Avi Tag, His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, pH7.4. |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
| Reference | 1. Roopenian D. et al. (2007) FcRn: the neonatal Fc receptor comes of age. Nat Rev Immunol. 7: 715-725. |
Background
FcRn is an unusual Fc receptor, the biological importance of which is only beginning to be fully appreciated. In addition to its critical role in the transfer of maternal IgG to the fetus or neonate, FcRn is the homeostatic receptor responsible for extending the serum half-life of IgG in adults. The exact site(s) of IgG protection from degradation has not been delineated in vivo, but both endothelial cells and bone-marrow-derived cells can extend the serum persistence of IgG. FcRn is also expressed in many other tissues in the adult animal, including barrier sites such as the blood–brain interface, the glomerular filter in the kidneys and the intestinal epithelium. FcRn expression at these sites merits further study with the goals of modulating specific IgG transport to promote host defence or to control immune-complex deposition.
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4.4 ★★★★★
Based on 437 reviews
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Product Reviews
★★★★★ 4
keyboard and case is phenomenal, trackpad is borderline unfunctional
Color: Black
I bought this case, because of the keyboard and trackpad, i wanted to use my ipad more like a laptop. the keyboard is phenomenal and certaintly better than other cheap ipad keyboards i have tried, I can actually use this one without having to repeatedly slam or hard press certain keys and can actually have a flow of typing. additionally, everything else regarding the case itself is amazing. it isnt cumbersome or bulky and it is very easy to swap between ipad and laptop mode on the fly. the trackpad however is genuinely unusable. the sensitivity on the trackpad is horrid and I cannot figure out how to change it, and additionally, clicking using the trackpad is outright impossible. you try to left click, it registers as a right click, or you try to click and it instead snaps your cursor to the bottom of the screen instead. it is also impossible to use any gesture functions with the trackpad, even something as simple as scrolling up and down or left to right is impossible. it is outright impossible to have any kind of workflow using the trackpad. it is unfortunately just a lot easier to use the keyboard and touch screen! its a shame that the keyboard and case itself is very nice too, so I will now have to spend more money on a separate mouse, which is additionally ANOTHER item i will have to carry around, just to make what I already bought work the way I expected.
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Reviewed in the United States on June 4, 2026
★★★★★ 5
Great quality at a great price range!
Color: Navy Blue
Works very well for the day to day. Great quality at a great price range. Would definitely buy again if needed.
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Reviewed in the United States on May 14, 2026
★★★★★ 5
Solid case.
Color: Sky-Blue
Love this case. Fits great and the color is great! The keyboard is nice and it even has a little spot for a stylist.
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Reviewed in the United States on June 3, 2026
★★★★★ 4
Cheap and good
Color: Black, Color: Black
I chose the color black and it gives a really nice look, especially with the multicolor led lights around the keys. It is very easy to clean and you can shut off the keyboard to prevent any mess with the iPad. The magnet is very nice and keeps the keyboard in place. The keyboard doesn’t easily slip or anything so it holds the iPad very well. Only bad thing is that over time the iPad begins to scrape off the pain and it leaves your keyboard with some white spots all over :/ but if looks isn’t something that you care about, this is the keyboard for you. Don’t use it for gaming because there is a delay in functionality when you press a key and then try to use the pad. Also, you have to press the keys a bit harder than the usual keyboard. But for the price? This is a great item! Definitely worth my money
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Reviewed in the United States on January 18, 2026
★★★★★ 5
Great quality at a remarkable price
Color: Navy Blue
I got an iPad and was looking for a cover to protect it. I came across this case that has a Bluetooth keyboard. It seems to be working great. It was less than $30 and had 4.5 stars with over 4k reviews.
The keyboard is magnetic and detachable, so I’ve got lots of configuration options. The keyboard pairs easily and allows you to use the iPad like a laptop. The point of an iPad a lot in one shot is kind of the touchscreen, but when I’m typing a lot of text as once (like now), it’s really nice to have a physical keyboard and touchpad. The keys are comfortably spaced and I’m comfortable typing on it. There is no additional setup for the keyboard besides pairing it to the iPad. At that point, all the cursor and keyboard features are immediately available.
The case is well built and has nice features like a slot to hold a stylus and multiple grooves to set your viewing angle. It’s configured to be used in landscape mode, but if for some reason you wanted to use it in portrait mode, you can pop the keyboard off to lay it flat. Especially for the price, this is an exceptionally nice iPad cover.
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Reviewed in the United States on May 8, 2026
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